Fat Bob's Smokehouse is one of The 15 Best Places for Southern Food in Buffalo.

1. Fat Bob's Smokehouse

8.4
41 Virginia Pl (Virginia St), Buffalo, NY
BBQ Joint · Allen · 57 tips and reviews

NickNick: Best macaroni and cheese in town!

Megan H.Megan H.: Cornbread, Mac n cheese, hush puppies and smashed potatoes are to die for!!!!!! Comfort food at its finest.

Derek M.Derek M: Forget Dinosaur BBQ, this is hands down, the best BBQ in Buffalo! Consistently amazing food and the Mac and Cheese is the best you'll ever have!

Toutant is one of The 15 Best Places for Southern Food in Buffalo.

2. Toutant

7.9
437 Ellicott St, Buffalo, NY
Cajun and Creole Restaurant · Central Business District · 17 tips and reviews

Carrie Yael R.Carrie Yael Rittenhouse: The " gris-gris" biscuit to start! The buttermilk fried chicken was to die for and ended with ooey gooey bourbon caramel cake! ! Fabulous..and try the "Packmule" yum!!!

Nicole J.Nicole Johnson: Everything was delicious but the Gris Gris Biscuit Sandwich was stupid delicious.

Jon S.Jon Spitz: Great service, vibe, cornbread and desert. Get the coffee themed desert and add liquor. You will NOT regret it.

Dinosaur Bar-B-Que is one of The 15 Best Places for Southern Food in Buffalo.

3. Dinosaur Bar-B-Que

8.5
301 Franklin St (btwn W Chippewa St & W Tupper St), Buffalo, NY
BBQ Joint · Central Business District · 58 tips and reviews

Kate O.Kate Onthetrack: Love it!! It's so good. The fried green tomatoes are the best, mouth watering pulled pork and ribs and they smoke the wings! Plus they have a take out counter!

Chris W.Chris W: Nice option to allow the kids to sample the Mac and Cheese first.

Michael C.Michael Constantine: The fried green tomatoes are really good here!

Shango New Orleans Bistro & Wine Bar is one of The 15 Best Places for Southern Food in Buffalo.

4. Shango New Orleans Bistro & Wine Bar

7.5
3260 Main St (near Heath St), Buffalo, NY
Cajun and Creole Restaurant · University · 36 tips and reviews

Alexis T.Alexis T.: Shango never disappoints!! My absolute favorite restaurant in Buffalo. The Mac N' Cheese is to die for!!!!!

Elle K.Elle Kwon: Try the Buttermilk Fried Chicken With Andouille Sausage Gravy - I love it.

Katie K.Katie K: Shrimp and grits are fantastic, and the pork belly appetizer is to die for.

Betty's Restaurant is one of The 15 Best Places for Southern Food in Buffalo.

5. Betty's Restaurant

8.9
370 Virginia St (at Cottage St), Buffalo, NY
Breakfast Spot · Allen · 60 tips and reviews

lexington J.lexington Jones: Shrimp and grits

D C.D Craft: Meatloaf sandwich, biscuits and gravy, home fries.

Laketa C.Laketa C.: Shrimp and Grits were good

Ballyhoo Links & Drinks is one of The 15 Best Places for Southern Food in Buffalo.

6. Ballyhoo Links & Drinks

8.5
211 South Park Ave (at Michigan Ave), Buffalo, NY
Bar · Buffalo River · 18 tips and reviews

Philip J.Philip Jarosz: The drinks are classic and well done. The sausage is amazing and don’t miss the Mac and cheese.

Melissa K.Melissa Kaita: The mac and cheese is 👌🏻

Caryn P.Caryn Poland: I am obsessed with this place! Everything is homemade, even the pickles :) the sausage, soups and slaw are the best in town.

The Dapper Goose is one of The 15 Best Places for Southern Food in Buffalo.

7. The Dapper Goose

8.6
491 Amherst St, Buffalo, NY
New American Restaurant · Black Rock · 3 tips and reviews

Matthew F.Matthew Ferguson: Cool spot with a nice craft cocktail list, New York cider, and Korean Fried Chicken to die for!

Jon S.Jon Spitz: The best burger in Buffalo. That cheese is killer on it. Also the blackened green beans are to die for. Don't skip dessert

John C.John Colglazier: The halibut is savory and flakey in all the right ways. Had a great local Blackbird Cider to top it all off. Great place

Bertha's Diner is one of The 15 Best Places for Southern Food in Buffalo.

8. Bertha's Diner

7.2
1430 Hertel Ave, Buffalo, NY
Diner · North Park · 19 tips and reviews

Ryan T.Ryan T.: Best biscuits and sausage gravy.

j l.j l: Chicken and Waffles are a must! Great breakfast joint. Cash only!

Bruised W.Bruised Wayne: Not the service. Waited an unusually long time for chicken and waffles that were only mediocre upon delivery. Small and cramped establishment. Not recommended.

Allen Street Hardware Cafe is one of The 15 Best Places for Southern Food in Buffalo.

9. Allen Street Hardware Cafe

8.3
245 Allen St (at College St), Buffalo, NY
Wine Bar · Allen · 61 tips and reviews

Robin C.Robin Carman: Fried chicken sandwich. If you eat meat, remember those three words.

Melissa C.Melissa Cool: Try any of there daily specials. There fried chicken is great.

Emma F.Emma Fabian: Best place in Buffalo. Possibly best place in the world.

Pano's On Elmwood is one of The 15 Best Places for Southern Food in Buffalo.

10. Pano's On Elmwood

7.5
1081 Elmwood Ave (btwn Forest & Bird), Buffalo, NY
Greek Restaurant · Albright · 91 tips and reviews

Mark D.Mark Degolyer: Lobster Mac and cheese is really disappointing. Everything else is fantastic though.

Amber Kay G.Amber Kay George: A heads up, they stopped serving biscuits and gravy on the weekends. So disappointing.

DJ J.DJ Jarak: I first visited Pano's last year and had their lobster macaroni and cheese. Amazing! I returned a few months later and had their Belgium waffles with blueberries. To die for.

The Phoenix is one of The 15 Best Places for Southern Food in Buffalo.

11. The Phoenix

7.6
269 Amherst St, Buffalo, NY
Gastropub · Black Rock · 13 tips and reviews

tessa l.tessa lowe: The hot pepper app and shrimp n grits were excellent.

Matthew A.Matthew Anthony: Buffalos new hidden gem. Food is unique and delicious. Try the blackened fish fry on Fridays and the phoenix tart for dessert.

Amanda B.Amanda Burlett-Cooley: Cayenne caramel torte was amazing, everything was amazing!

Amy's Place is one of The 15 Best Places for Southern Food in Buffalo.

12. Amy's Place

8.1
3234 Main St (at Merrimac St), Buffalo, NY
Vegan and Vegetarian Restaurant · University · 72 tips and reviews

Christina O.Christina O'Reilly: Vegan Mac & Cheese is out of this world!

Enrico S.Enrico S: Great vegetarian food. Big portion and cheap. Cash only but ATM inside.

CaydenCayden: Check out breakfast at Amy's between 6 and 9. $1.99 eggs, toast, and home fries!

Pearl Street Grill & Brewery is one of The 15 Best Places for Southern Food in Buffalo.

13. Pearl Street Grill & Brewery

8.4
76 Pearl St (at Seneca St), Buffalo, NY
Brewery · Central Business District · 168 tips and reviews

Erika H.Erika Heyer: Mac n cheese is great!

Tom O.Tom O'C: The loaded fries make for a great appetizer for a group. So good we ordered them as a meal the next visit!!

Alex N.Alex Nesselbeck: Get the trainwreck!

Niagara Cafe is one of The 15 Best Places for Southern Food in Buffalo.

14. Niagara Cafe

8.3
525 Niagara St (at Pennsylvania St.), Buffalo, NY
Latin American Restaurant · West Side · 22 tips and reviews

Eddie R.Eddie R.: A genuine Puerto Rican family-run restaurant that serves delicious, fresh -- almost home-made -- PR cuisine. Highly recommended.

Lisa G.Lisa Griffin: Got some great rice and beans. Yummy!!!

Clark D.Clark Dever: rotissarie chicken is amazing.

The Burning Buffalo Pub & Grill is one of The 15 Best Places for Southern Food in Buffalo.

15. The Burning Buffalo Pub & Grill

7.1
1504 Hertel Ave, Buffalo, NY
American Restaurant · North Park · 2 tips and reviews

Jon S.Jon Spitz: The fish fry and Mac cheese are fantastic.

Chris B.Chris Barning: Loved the Steak Burger